Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. [electronic resource]
Producer: 20140401Description: 1728-37 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Azocines -- pharmacology
- Baculoviral IAP Repeat-Containing 3 Protein
- Benzhydryl Compounds -- pharmacology
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Carcinoma
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor
- Drug Synergism
- Female
- Humans
- Inhibitor of Apoptosis Proteins -- antagonists & inhibitors
- Intracellular Signaling Peptides and Proteins -- chemistry
- Mice, Nude
- Mitochondrial Proteins -- chemistry
- Molecular Mimicry
- Nasopharyngeal Carcinoma
- Nasopharyngeal Neoplasms -- drug therapy
- Neoplastic Stem Cells -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Triazoles -- pharmacology
- Ubiquitin-Protein Ligases
- X-Linked Inhibitor of Apoptosis Protein -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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