Histone deacetylase (HDAC) inhibitors as single agents induce multiple myeloma cell death principally through the inhibition of class I HDAC. [electronic resource]
Producer: 20131017Description: 559-62 p. digitalISSN:- 1365-2141
- Acetylation -- drug effects
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor -- drug effects
- Depsipeptides -- pharmacology
- Drug Screening Assays, Antitumor
- Histone Deacetylase Inhibitors -- pharmacology
- Histones -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Indoles -- pharmacology
- Multiple Myeloma -- enzymology
- Neoplasm Proteins -- antagonists & inhibitors
- Panobinostat
- Protein Processing, Post-Translational -- drug effects
- Pyrimidines -- pharmacology
- Tubulin -- metabolism
- Tumor Cells, Cultured -- drug effects
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Publication Type: Comparative Study; Letter; Research Support, Non-U.S. Gov't
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