RNA interference-mediated silencing of NANOG leads to reduced proliferation and self-renewal, cell cycle arrest and apoptosis in T-cell acute lymphoblastic leukemia cells via the p53 signaling pathway. [electronic resource]
Producer: 20131017Description: 1170-7 p. digitalISSN:- 1873-5835
- Apoptosis
- Biomarkers, Tumor -- genetics
- Blotting, Western
- Cell Cycle Checkpoints
- Cell Differentiation
- Cell Proliferation
- Colony-Forming Units Assay
- Gene Expression Profiling
- Homeodomain Proteins -- antagonists & inhibitors
- Humans
- Nanog Homeobox Protein
- Oligonucleotide Array Sequence Analysis
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- RNA Interference
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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