KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells. [electronic resource]
Producer: 20140206Description: 4406-17 p. digitalISSN:- 1538-7445
- Animals
- Antioxidants -- metabolism
- Carrier Proteins -- metabolism
- Cell Line
- Cell Line, Tumor
- Epithelial Cells -- drug effects
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Kelch-Like ECH-Associated Protein 1
- Male
- Mice
- Mice, Nude
- Mitochondrial Proteins -- metabolism
- NF-E2-Related Factor 2 -- metabolism
- Oxidation-Reduction
- Oxidative Stress -- drug effects
- Phosphoprotein Phosphatases
- Prostatic Neoplasms -- drug therapy
- Radiation Tolerance
- Radiation-Sensitizing Agents -- pharmacology
- Random Allocation
- Reactive Oxygen Species -- metabolism
- Sesquiterpenes -- pharmacology
- Thioredoxins -- metabolism
- Ubiquitin -- metabolism
- Xenograft Model Antitumor Assays
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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