Identification and selective degradation of neopeptide-containing truncated mutant proteins in the tumors with high microsatellite instability. [electronic resource]
Producer: 20140128Description: 3369-82 p. digitalISSN:- 1557-3265
- Adult
- Aged
- Aged, 80 and over
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Centrosome -- metabolism
- Codon, Nonsense
- Colorectal Neoplasms -- genetics
- Exons
- Female
- Frameshift Mutation
- Gene Expression
- Gene Expression Profiling
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Male
- Membrane Proteins -- genetics
- Microsatellite Instability
- Middle Aged
- Mutant Proteins -- genetics
- Myristoylated Alanine-Rich C Kinase Substrate
- Neoplasm Grading
- Neoplasm Staging
- Neoplasms -- genetics
- Polyribosomes -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- Protein Transport
- Protein-Tyrosine Kinases -- genetics
- Proteolysis
- RNA, Messenger -- genetics
- Transcription Factor 7-Like 2 Protein -- genetics
- Ubiquitination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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