The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78. [electronic resource]
Producer: 20131217Description: e63414 p. digitalISSN:- 1932-6203
- Antibodies, Monoclonal -- pharmacology
- Apoptosis -- drug effects
- Bone Marrow -- drug effects
- Cell Line, Tumor
- Cell Membrane -- drug effects
- Complement Activation -- drug effects
- Complement C1q -- metabolism
- Endoplasmic Reticulum Chaperone BiP
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Immunoglobulin M -- pharmacology
- Immunohistochemistry
- Multiple Myeloma -- pathology
- Protein Binding -- drug effects
- Reproducibility of Results
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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