Sphingosine 1-phosphate counteracts the effects of interleukin-1β in human chondrocytes. [electronic resource]
Producer: 20131017Description: 2113-22 p. digitalISSN:- 1529-0131
- ADAM Proteins -- metabolism
- ADAMTS4 Protein
- Cartilage, Articular -- drug effects
- Cells, Cultured
- Chondrocytes -- drug effects
- Drug Antagonism
- Gene Knockdown Techniques
- Gene Silencing
- Humans
- Interleukin-1beta -- metabolism
- Lysophospholipids -- pharmacology
- Matrix Metalloproteinase 13 -- metabolism
- NF-kappa B -- metabolism
- Nitric Oxide Synthase Type II -- antagonists & inhibitors
- Phosphorylation
- Procollagen N-Endopeptidase -- metabolism
- RNA, Small Interfering -- genetics
- Receptors, Lysosphingolipid -- genetics
- Signal Transduction
- Sphingosine -- analogs & derivatives
- Sphingosine-1-Phosphate Receptors
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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