BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways. [electronic resource]
Producer: 20140716Description: 1713-24 p. digitalISSN:- 1476-5594
- Adaptor Proteins, Signal Transducing -- biosynthesis
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- biosynthesis
- Autophagy -- physiology
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Death -- drug effects
- Cell Line, Tumor
- HEK293 Cells
- Humans
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors -- pharmacology
- Proteolysis -- drug effects
- Pyrazines -- pharmacology
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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