Synthesis of proline analogues as potent and selective cathepsin S inhibitors. [electronic resource]
Producer: 20131209Description: 3140-4 p. digitalISSN:- 1464-3405
- Animals
- Arthritis -- chemically induced
- Benzoxazoles -- chemical synthesis
- Cathepsin B -- antagonists & inhibitors
- Cathepsin K -- antagonists & inhibitors
- Cathepsins -- antagonists & inhibitors
- Collagen -- toxicity
- Disease Models, Animal
- Dogs
- Enzyme Inhibitors -- chemical synthesis
- Half-Life
- Humans
- Mice
- Mice, Inbred ICR
- Microsomes -- metabolism
- Proline -- analogs & derivatives
- Protein Binding
- Rats
- Rats, Sprague-Dawley
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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