Pentoxifylline inhibits melanoma tumor growth and angiogenesis by targeting STAT3 signaling pathway. [electronic resource]
Producer: 20140121Description: 399-405 p. digitalISSN:- 1950-6007
- Angiogenesis Inhibitors -- administration & dosage
- Animals
- Cell Line, Tumor
- Dose-Response Relationship, Drug
- Female
- Humans
- Melanoma -- drug therapy
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Neovascularization, Physiologic -- drug effects
- Pentoxifylline -- administration & dosage
- Phosphodiesterase Inhibitors -- administration & dosage
- Phosphorylation -- drug effects
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Skin Neoplasms -- drug therapy
- Tumor Microenvironment -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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