Specificity redirection by CAR with human VEGFR-1 affinity endows T lymphocytes with tumor-killing ability and anti-angiogenic potency. [electronic resource]
Producer: 20140422Description: 970-8 p. digitalISSN:- 1476-5462
- Animals
- Antigens, Neoplasm -- immunology
- Cell Death
- Cells, Cultured
- Cytotoxicity, Immunologic
- Electroporation
- Genetic Therapy -- methods
- HeLa Cells
- Humans
- Immunotherapy, Adoptive
- Mice
- Mice, SCID
- Neoplasms, Experimental -- immunology
- Receptors, Antigen, T-Cell -- immunology
- Recombinant Fusion Proteins -- immunology
- T-Cell Antigen Receptor Specificity
- T-Lymphocytes -- immunology
- Vascular Endothelial Growth Factor Receptor-1 -- immunology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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