Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anticancer effects. [electronic resource]
Producer: 20131217Description: 2050-60 p. digitalISSN:- 1460-2180
- Adaptor Proteins, Signal Transducing -- antagonists & inhibitors
- Alkaloids -- administration & dosage
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Cell Cycle Proteins
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- HCT116 Cells
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Microtubule-Associated Proteins -- metabolism
- Neoplasms -- genetics
- Phenanthrenes -- administration & dosage
- Phosphoproteins -- antagonists & inhibitors
- Quinolizidines -- administration & dosage
- TOR Serine-Threonine Kinases -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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