BMP-6 in renal cell carcinoma promotes tumor proliferation through IL-10-dependent M2 polarization of tumor-associated macrophages. [electronic resource]
Producer: 20130830Description: 3604-14 p. digitalISSN:- 1538-7445
- Animals
- Bone Morphogenetic Protein 6 -- genetics
- Carcinoma, Renal Cell -- metabolism
- Cell Line
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Clodronic Acid -- pharmacology
- Doxycycline -- pharmacology
- Humans
- Immunoblotting
- Interleukin-10 -- genetics
- Kaplan-Meier Estimate
- Kidney Neoplasms -- metabolism
- Macrophages -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Microscopy, Fluorescence
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- STAT3 Transcription Factor -- genetics
- Smad5 Protein -- genetics
- Tumor Burden -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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