Pathophysiological roles of nuclear factor kappaB (NF-kB) in pulmonary arterial hypertension: effects of synthetic selective NF-kB inhibitor IMD-0354. [electronic resource]
Producer: 20140131Description: 35-43 p. digitalISSN:- 1755-3245
- Animals
- Antihypertensive Agents -- pharmacology
- Apoptosis -- drug effects
- Benzamides -- pharmacology
- Cell Proliferation -- drug effects
- Cells, Cultured
- Chemokine CCL2 -- metabolism
- Disease Models, Animal
- Familial Primary Pulmonary Hypertension
- Feedback, Physiological
- Fibroblast Growth Factor 2 -- genetics
- Hypertension, Pulmonary -- chemically induced
- Male
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Monocrotaline
- Muscle, Smooth, Vascular -- drug effects
- Myocytes, Smooth Muscle -- drug effects
- NF-kappa B -- antagonists & inhibitors
- Pulmonary Artery -- drug effects
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Time Factors
- Tissue Plasminogen Activator -- genetics
- Transcription Factor RelA -- antagonists & inhibitors
- Ventricular Function, Right -- drug effects
- Ventricular Pressure -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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