Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis. [electronic resource]
Producer: 20131105Description: 52 p. digitalISSN:- 1742-2094
- Amyotrophic Lateral Sclerosis -- therapy
- Animals
- Blotting, Western
- Bone Marrow Cells -- physiology
- Bone Marrow Transplantation -- methods
- Cell Count
- Cell- and Tissue-Based Therapy
- Disease Progression
- Enzyme-Linked Immunosorbent Assay
- Gene Dosage
- Humans
- Immunohistochemistry
- Macrophage Activation -- physiology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Microglia -- physiology
- Motor Neurons -- physiology
- Neurons -- physiology
- Spinal Cord -- pathology
- Stromal Cells -- physiology
- Superoxide Dismutase -- genetics
- Superoxide Dismutase-1
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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