Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override. [electronic resource]
Producer: 20131216Description: 1588-97 p. digitalISSN:- 1551-4005
- Animals
- Antineoplastic Agents -- toxicity
- Apoptosis -- drug effects
- CHO Cells
- Cell Line, Tumor
- Centromere -- metabolism
- Checkpoint Kinase 1
- Comet Assay
- Cricetinae
- Cricetulus
- DNA Damage -- drug effects
- DNA Topoisomerases, Type II -- chemistry
- Deoxycytidine -- analogs & derivatives
- Doxorubicin -- toxicity
- Etoposide -- toxicity
- G2 Phase Cell Cycle Checkpoints -- drug effects
- HeLa Cells
- Humans
- Kinetochores -- metabolism
- Mitosis
- Protein Kinases -- chemistry
- S Phase Cell Cycle Checkpoints -- drug effects
- Staurosporine -- analogs & derivatives
- Topoisomerase II Inhibitors -- pharmacology
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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