Parg deficiency confers radio-sensitization through enhanced cell death in mouse ES cells exposed to various forms of ionizing radiation. [electronic resource]
Producer: 20130827Description: 100-6 p. digitalISSN:- 1090-2104
- Animals
- Apoptosis -- genetics
- Carbon
- Cell Survival -- drug effects
- Cells, Cultured
- DNA Breaks, Double-Stranded -- radiation effects
- Dose-Response Relationship, Radiation
- Embryonic Stem Cells -- cytology
- Flow Cytometry
- Gamma Rays
- Glycoside Hydrolases -- deficiency
- Heavy Ions
- Histones -- metabolism
- Immunoblotting
- Mice
- Mice, Knockout
- Phosphorylation -- radiation effects
- Poly Adenosine Diphosphate Ribose -- metabolism
- Poly(ADP-ribose) Polymerases -- deficiency
- Radiation, Ionizing
- Time Factors
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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