Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer. [electronic resource]
Producer: 20131111Description: e61342 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Benzoquinones -- pharmacology
- Breast Neoplasms -- blood supply
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- Drug Synergism
- Female
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Mice
- Neoplasm Invasiveness
- Neovascularization, Pathologic -- drug therapy
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Tamoxifen -- pharmacology
- X-Linked Inhibitor of Apoptosis Protein -- metabolism
- Xenograft Model Antitumor Assays
- bcl-Associated Death Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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