Inactivation of PTEN increases ABCG2 expression and the side population through the PI3K/Akt pathway in adult acute leukemia. [electronic resource]
Producer: 20130815Description: 96-105 p. digitalISSN:- 1872-7980
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- metabolism
- Adolescent
- Adult
- Aged
- Antineoplastic Agents -- pharmacology
- Case-Control Studies
- Chromones -- pharmacology
- Female
- Gene Expression Regulation, Leukemic
- HL-60 Cells
- Humans
- Jurkat Cells
- Leukemia, Myeloid, Acute -- metabolism
- Male
- Middle Aged
- Mitoxantrone -- pharmacology
- Morpholines -- pharmacology
- Neoplasm Proteins -- metabolism
- PTEN Phosphohydrolase -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- Sirolimus -- pharmacology
- Stem Cells -- cytology
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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