The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study. [electronic resource]
Producer: 20131031Description: 505-12 p. digitalISSN:- 1558-3597
- Aged
- Aryl Hydrocarbon Hydroxylases -- genetics
- Aspirin -- therapeutic use
- Clopidogrel
- Coronary Artery Disease -- drug therapy
- Cross-Over Studies
- Cytochrome P-450 CYP1A2 -- metabolism
- Cytochrome P-450 CYP2C19
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Humans
- Male
- Middle Aged
- Piperazines -- pharmacokinetics
- Platelet Aggregation Inhibitors -- pharmacokinetics
- Platelet Function Tests
- Prasugrel Hydrochloride
- Prospective Studies
- Purinergic P2Y Receptor Antagonists -- pharmacokinetics
- Smoking -- metabolism
- Thiophenes -- pharmacokinetics
- Ticlopidine -- analogs & derivatives
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Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
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