Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen. [electronic resource]
Producer: 20131023Description: 39-49 p. digitalISSN:- 1573-7217
- Adult
- Aged
- Antineoplastic Agents -- therapeutic use
- Aromatase Inhibitors -- therapeutic use
- Breast Neoplasms -- drug therapy
- Class I Phosphatidylinositol 3-Kinases
- DNA Mutational Analysis
- Disease-Free Survival
- Drug Resistance, Neoplasm -- genetics
- Female
- Humans
- Kaplan-Meier Estimate
- Middle Aged
- Mutation
- Phosphatidylinositol 3-Kinases -- genetics
- Prognosis
- Receptor, ErbB-2 -- genetics
- Receptors, Estrogen -- genetics
- Receptors, Progesterone -- genetics
- Retrospective Studies
- Tamoxifen -- therapeutic use
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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