Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expression in gastrointestinal stromal tumors. [electronic resource]
Producer: 20140527Description: 1872-6 p. digitalISSN:- 1476-5594
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- Cell Survival
- Chaperonins -- metabolism
- Drug Resistance, Neoplasm
- Gastrointestinal Stromal Tumors -- metabolism
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Gene Library
- HSP90 Heat-Shock Proteins -- metabolism
- Humans
- Lentivirus -- metabolism
- Oncogenes
- Pentacyclic Triterpenes
- Protein Kinase Inhibitors -- chemistry
- Proto-Oncogene Proteins c-kit -- metabolism
- RNA, Small Interfering -- metabolism
- Triterpenes -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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