Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells. [electronic resource]
Producer: 20131104Description: 305-11 p. digitalISSN:- 1950-6007
- Antimetabolites, Antineoplastic -- pharmacology
- Azacitidine -- analogs & derivatives
- Blotting, Western
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Decitabine
- Enzyme Inhibitors -- pharmacology
- Flow Cytometry
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Knockdown Techniques
- HCT116 Cells
- Humans
- Lung Neoplasms -- drug therapy
- M Phase Cell Cycle Checkpoints -- drug effects
- RNA, Small Interfering -- administration & dosage
- Stomach Neoplasms -- drug therapy
- Tumor Suppressor Protein p53 -- genetics
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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