Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells. [electronic resource]
Producer: 20130612Description: 2639-49 p. digitalISSN:- 1538-7445
- ADP-Ribosylation Factors -- metabolism
- Activating Transcription Factor 4 -- genetics
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Circadian Rhythm -- genetics
- Dose-Response Relationship, Drug
- Male
- Mice
- Mice, Knockout
- Neoplasms -- genetics
- Protein Stability
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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