Intestinal absorption mechanism of mirabegron, a potent and selective β₃-adrenoceptor agonist: involvement of human efflux and/or influx transport systems. [electronic resource]
Producer: 20131216Description: 1783-94 p. digitalISSN:- 1543-8392
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- metabolism
- Acetanilides -- pharmacokinetics
- Adrenergic beta-3 Receptor Agonists -- pharmacokinetics
- Animals
- Biological Availability
- Biological Transport, Active
- Caco-2 Cells
- Cell Membrane Permeability
- Female
- HEK293 Cells
- Humans
- Hydrogen-Ion Concentration
- Intestinal Absorption -- physiology
- LLC-PK1 Cells
- Neoplasm Proteins -- metabolism
- Oocytes -- metabolism
- Organic Anion Transporters -- metabolism
- Peptide Transporter 1
- Recombinant Proteins -- metabolism
- Swine
- Symporters -- metabolism
- Thiazoles -- pharmacokinetics
- Urinary Bladder, Overactive -- drug therapy
- Xenopus laevis
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Publication Type: Journal Article
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