A novel PEGylated liposome-encapsulated SANT75 suppresses tumor growth through inhibiting hedgehog signaling pathway. [electronic resource]
Producer: 20130916Description: e60266 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Compounding
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, Reporter
- Green Fluorescent Proteins
- Humans
- Liposomes -- chemistry
- Mice
- Mice, Inbred C57BL
- Oncogene Proteins -- antagonists & inhibitors
- Polyethylene Glycols -- chemistry
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Smoothened Receptor
- Trans-Activators -- antagonists & inhibitors
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
- Zebrafish
- Zinc Finger Protein GLI1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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