Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. [electronic resource]
Producer: 20130827Description: 1561-7 p. digitalISSN:- 1524-4636
- Angiogenesis Inducing Agents -- administration & dosage
- Animals
- Apolipoproteins E -- deficiency
- Autoradiography
- Biomarkers -- blood
- Blood Flow Velocity
- Blood-Brain Barrier -- drug effects
- Cadherins -- metabolism
- Capillaries -- drug effects
- Capillary Permeability -- drug effects
- Cerebrovascular Circulation -- drug effects
- Disease Models, Animal
- Endothelial Cells -- drug effects
- Extracellular Matrix -- metabolism
- Humans
- Hyperlipidemias -- blood
- Infusion Pumps, Implantable
- Laser-Doppler Flowmetry
- Lipids -- blood
- Luminescent Measurements
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neovascularization, Physiologic -- drug effects
- Neuroprotective Agents -- administration & dosage
- Pericytes -- drug effects
- Stroke -- blood
- Time Factors
- Vascular Endothelial Growth Factor A -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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