Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity. [electronic resource]
Producer: 20130712Description: 12654-66 p. digitalISSN:- 1083-351X
- Aggrecans -- biosynthesis
- Animals
- Cell Hypoxia -- genetics
- Cell Line
- Collagen Type II -- biosynthesis
- Connective Tissue Growth Factor -- genetics
- Gene Expression Regulation
- Gene Knockdown Techniques
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Intervertebral Disc -- metabolism
- Mice
- Mice, Mutant Strains
- Rats
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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