Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold. [electronic resource]
Producer: 20130607Description: 138-51 p. digitalISSN:- 1097-4199
- Animals
- Calcitonin Gene-Related Peptide -- genetics
- Capsaicin -- pharmacology
- Cold Temperature
- Diphtheria Toxin -- pharmacology
- Excitatory Postsynaptic Potentials -- drug effects
- Female
- Ganglia, Spinal -- cytology
- Gene Expression Regulation -- drug effects
- Green Fluorescent Proteins -- genetics
- Histamine -- adverse effects
- Hot Temperature
- In Vitro Techniques
- Lectins -- metabolism
- Male
- Mice
- Mice, Transgenic
- Neurofilament Proteins -- metabolism
- Pruritus -- chemically induced
- Pyrimidinones -- pharmacology
- Reaction Time -- drug effects
- Receptors, Calcitonin Gene-Related Peptide -- metabolism
- Sensory Receptor Cells -- drug effects
- Sensory Thresholds -- physiology
- Skin -- innervation
- Sural Nerve -- drug effects
- TRPM Cation Channels -- metabolism
- TRPV Cation Channels -- metabolism
- Time Factors
- Ubiquitin Thiolesterase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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