The BH3-only protein Puma plays an essential role in p53-mediated apoptosis of chronic lymphocytic leukemia cells. [electronic resource]
Producer: 20140609Description: 2712-9 p. digitalISSN:- 1029-2403
- ADP-ribosyl Cyclase 1 -- metabolism
- Aged
- Aged, 80 and over
- Antineoplastic Agents -- therapeutic use
- Apoptosis
- Apoptosis Regulatory Proteins -- genetics
- Bcl-2-Like Protein 11
- Cell Line, Tumor
- Female
- Gene Expression Regulation, Leukemic
- Humans
- Immunoglobulin Heavy Chains -- genetics
- Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
- Male
- Membrane Proteins -- genetics
- Middle Aged
- Mitochondrial Membrane Transport Proteins
- Mutation
- Neoplasm Staging
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Tumor Suppressor Protein p53 -- genetics
- Vidarabine -- analogs & derivatives
- ZAP-70 Protein-Tyrosine Kinase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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