A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses. [electronic resource]
Producer: 20140219Description: 446-54 p. digitalISSN:- 1468-2060
- Adipogenesis -- drug effects
- Adult
- Animals
- Biopsy
- Cells, Cultured
- Collagen -- biosynthesis
- Disease Models, Animal
- Drug Evaluation, Preclinical -- methods
- Female
- Fibroblasts -- drug effects
- Fibrosis
- Humans
- Infant, Newborn
- Mice
- Mice, Inbred C57BL
- Oleanolic Acid -- analogs & derivatives
- Organ Culture Techniques
- PPAR gamma -- agonists
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Scleroderma, Systemic -- drug therapy
- Signal Transduction -- drug effects
- Skin -- drug effects
- Transforming Growth Factor beta -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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