Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis. [electronic resource]
Producer: 20141114Description: 305-16 p. digitalISSN:- 1435-5922
- Animals
- Cell Proliferation
- Cholagogues and Choleretics -- pharmacology
- Cyclin A2 -- genetics
- Cyclin B1 -- genetics
- Cyclin D1 -- genetics
- Cyclins -- genetics
- DNA Replication
- DNA-Binding Proteins -- genetics
- Diet, High-Fat -- adverse effects
- Endoplasmic Reticulum -- drug effects
- Endoplasmic Reticulum Chaperone BiP
- Fatty Liver -- etiology
- Forkhead Box Protein M1
- Forkhead Transcription Factors -- genetics
- Gene Expression -- drug effects
- Heat-Shock Proteins -- genetics
- Hepatectomy
- Hepatocytes -- cytology
- Liver Regeneration -- drug effects
- MAP Kinase Signaling System
- Male
- Mice
- Mice, Inbred C57BL
- Organ Size
- Phosphorylation
- Proliferating Cell Nuclear Antigen -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Messenger -- metabolism
- Regulatory Factor X Transcription Factors
- Stress, Physiological
- Taurochenodeoxycholic Acid -- pharmacology
- Time Factors
- Transcription Factors -- genetics
- Unfolded Protein Response
- eIF-2 Kinase -- genetics
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Publication Type: Journal Article
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