Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents. [electronic resource]
Producer: 20140117Description: 712-23 p. digitalISSN:- 1520-4812
- Animals
- Cyclooxygenase 2 -- metabolism
- Cyclooxygenase Inhibitors -- chemical synthesis
- Dose-Response Relationship, Drug
- Drug Design
- Fluorescent Dyes -- chemical synthesis
- Humans
- Mice
- Mice, Nude
- Molecular Imaging
- Molecular Structure
- Neoplasms, Experimental -- drug therapy
- Optical Phenomena
- Structure-Activity Relationship
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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