Gli as a novel therapeutic target in malignant pleural mesothelioma. [electronic resource]
Producer: 20130904Description: e57346 p. digitalISSN:- 1932-6203
- Aged
- Anilides -- pharmacology
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Down-Regulation -- drug effects
- Drug Synergism
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Glutamates -- pharmacology
- Guanine -- analogs & derivatives
- Hedgehog Proteins -- metabolism
- Humans
- Kruppel-Like Transcription Factors -- antagonists & inhibitors
- Male
- Mesothelioma -- drug therapy
- Mice
- Mice, Nude
- Molecular Targeted Therapy
- Nuclear Proteins -- antagonists & inhibitors
- Pemetrexed
- Pleural Neoplasms -- drug therapy
- Pyridines -- pharmacology
- RNA, Small Interfering -- metabolism
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Smoothened Receptor
- Transcription Factors -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
- Zinc Finger Protein GLI1
- Zinc Finger Protein Gli2
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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