The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis. [electronic resource]
Producer: 20140512Description: 1638-48 p. digitalISSN:- 1613-4133
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Colonic Neoplasms -- genetics
- Curcumin -- pharmacology
- Down-Regulation
- Drug Resistance, Neoplasm -- drug effects
- Fluorouracil -- pharmacology
- Gene Expression Regulation, Neoplastic
- HT29 Cells
- Humans
- MicroRNAs -- antagonists & inhibitors
- Plasmids -- genetics
- RNA Interference -- drug effects
- RNA, Small Interfering -- genetics
- Reactive Oxygen Species -- metabolism
- Repressor Proteins -- genetics
- Signal Transduction
- Sp Transcription Factors -- antagonists & inhibitors
- Transfection
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Publication Type: Journal Article
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