Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease. [electronic resource]
Producer: 20130618Description: 597-605 p. digitalISSN:- 1541-6100
- Alzheimer Disease -- diet therapy
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- metabolism
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Brain -- drug effects
- Dietary Supplements
- Disease Models, Animal
- Ellagic Acid -- pharmacology
- Fruit
- Hydrolyzable Tannins -- pharmacology
- Lythraceae -- chemistry
- Male
- Maze Learning
- Memory -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Microglia -- drug effects
- NFATC Transcription Factors -- metabolism
- Phytotherapy
- Plant Extracts -- pharmacology
- Plaque, Amyloid -- metabolism
- Polyphenols -- pharmacology
- Presenilin-1 -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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