Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit. [electronic resource]
Producer: 20131021Description: 1105-18 p. digitalISSN:- 1551-4005
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- deficiency
- Cell Line
- Checkpoint Kinase 1
- DNA Damage -- radiation effects
- DNA Repair
- DNA-Binding Proteins -- deficiency
- G2 Phase Cell Cycle Checkpoints -- radiation effects
- HEK293 Cells
- Humans
- M Phase Cell Cycle Checkpoints -- radiation effects
- Phosphorylation
- Protein Kinases -- chemistry
- Protein Phosphatase 2 -- metabolism
- Protein Serine-Threonine Kinases -- deficiency
- RNA Interference
- RNA, Small Interfering -- metabolism
- Radiation, Ionizing
- Signal Transduction
- Tumor Suppressor Proteins -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Intramural
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