Insulin-mediated oxidative stress and DNA damage in LLC-PK1 pig kidney cell line, female rat primary kidney cells, and male ZDF rat kidneys in vivo. [electronic resource]
Producer: 20130506Description: 1434-43 p. digitalISSN:- 1945-7170
- Animals
- Antioxidants -- pharmacology
- Cells, Cultured
- Comet Assay
- DNA Damage
- Female
- HL-60 Cells -- drug effects
- Humans
- Hyperinsulinism -- complications
- Hypoglycemic Agents -- adverse effects
- Insulin -- adverse effects
- Kidney -- cytology
- LLC-PK1 Cells -- drug effects
- Male
- Neoplasms -- complications
- Oncogene Protein v-akt -- drug effects
- Oxidative Stress
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Rats
- Reactive Oxygen Species -- metabolism
- Receptor, IGF Type 1 -- antagonists & inhibitors
- Receptor, Insulin -- antagonists & inhibitors
- Swine
- Tumor Suppressor Protein p53 -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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