PRAME-induced inhibition of retinoic acid receptor signaling-mediated differentiation--a possible target for ATRA response in AML without t(15;17). [electronic resource]
Producer: 20131112Description: 2562-71 p. digitalISSN:- 1557-3265
- Antigens, Neoplasm -- physiology
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Cell Differentiation
- Cell Proliferation
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 17
- Clinical Trials, Phase III as Topic
- Gene Expression Regulation, Leukemic
- Gene Knockdown Techniques
- Humans
- K562 Cells
- Kaplan-Meier Estimate
- Leukemia, Myeloid, Acute -- drug therapy
- Nucleophosmin
- RNA, Small Interfering -- genetics
- Randomized Controlled Trials as Topic
- Receptors, Retinoic Acid -- metabolism
- Signal Transduction
- Transcriptome
- Translocation, Genetic
- Treatment Outcome
- Tretinoin -- administration & dosage
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.