The role of the Hsp90/Akt pathway in myocardial calpain-induced caspase-3 activation and apoptosis during sepsis. [electronic resource]
Producer: 20130708Description: 8 p. digitalISSN:- 1471-2261
- Acrylates -- pharmacology
- Androstadienes -- pharmacology
- Animals
- Apoptosis
- Benzoquinones -- pharmacology
- Calpain -- antagonists & inhibitors
- Caspase 3 -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- Dipeptides -- pharmacology
- Disease Models, Animal
- Enzyme Activation
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- In Situ Nick-End Labeling
- Lactams, Macrocyclic -- pharmacology
- Lipopolysaccharides
- Male
- Mice
- Mice, Inbred C57BL
- Myocardium -- enzymology
- Phosphatidylinositol 3-Kinase -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Sepsis -- chemically induced
- Signal Transduction -- drug effects
- Time Factors
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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