Inhibition of BET bromodomain targets genetically diverse glioblastoma. [electronic resource]
Producer: 20130927Description: 1748-59 p. digitalISSN:- 1557-3265
- Animals
- Azepines -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Disease Models, Animal
- Disease Progression
- Drug Resistance, Neoplasm -- genetics
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Knockdown Techniques
- Glioblastoma -- drug therapy
- Humans
- Mice
- Protein Kinase Inhibitors -- administration & dosage
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-myc -- metabolism
- RNA Interference
- Signal Transduction -- drug effects
- Transcription, Genetic -- drug effects
- Triazoles -- administration & dosage
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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