Profiling pathway-specific novel therapeutics in preclinical assessment for central nervous system atypical teratoid rhabdoid tumors (CNS ATRT): favorable activity of targeting EGFR- ErbB2 signaling with lapatinib. [electronic resource]
Producer: 20131223Description: 497-512 p. digitalISSN:- 1878-0261
- Animals
- Antineoplastic Agents -- therapeutic use
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Central Nervous System Neoplasms -- drug therapy
- Child
- ErbB Receptors -- metabolism
- Female
- Humans
- Infant
- Lapatinib
- Male
- Mice
- Molecular Targeted Therapy
- Quinazolines -- therapeutic use
- Receptor, ErbB-2 -- metabolism
- Rhabdoid Tumor -- drug therapy
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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