NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w. [electronic resource]
Producer: 20130620Description: 1085-95 p. digitalISSN:- 0006-3002
- Apoptosis -- genetics
- Apoptosis Regulatory Proteins -- genetics
- Cell Survival -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Silencing
- HeLa Cells
- Humans
- I-kappa B Proteins -- pharmacology
- Mitochondria
- Myeloid Cell Leukemia Sequence 1 Protein
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Tumor Necrosis Factor-alpha -- metabolism
- bcl-X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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