Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase. [electronic resource]
Producer: 20130515Description: 165-70 p. digitalISSN:- 1881-1469
- Aclarubicin -- administration & dosage
- Alkyl and Aryl Transferases -- drug effects
- Antibiotics, Antineoplastic -- administration & dosage
- Carcinoma, Squamous Cell -- drug therapy
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Cell Movement -- drug effects
- Epidermal Growth Factor -- administration & dosage
- Farnesyltranstransferase -- antagonists & inhibitors
- Genes, ras -- drug effects
- Geranylgeranyl-Diphosphate Geranylgeranyltransferase -- drug effects
- Humans
- Inhibitory Concentration 50
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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