(E)-4-aryl-4-oxo-2-butenoic acid amides, chalcone-aroylacrylic acid chimeras: design, antiproliferative activity and inhibition of tubulin polymerization. [electronic resource]
Producer: 20131017Description: 40-50 p. digitalISSN:- 1768-3254
- Acrylates -- chemistry
- Amides -- chemistry
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chalcone -- chemistry
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Fatty Acids, Monounsaturated -- chemistry
- HeLa Cells
- Humans
- K562 Cells
- Male
- Mice
- Molecular Structure
- Polymerization -- drug effects
- Structure-Activity Relationship
- Tubulin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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