Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells. [electronic resource]
Producer: 20130724Description: e54073 p. digitalISSN:- 1932-6203
- Animals
- Blotting, Western
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Cell Line
- Cell Line, Tumor
- Cell Movement -- drug effects
- Chemokine CCL2 -- genetics
- Coculture Techniques
- Fatty Acids, Unsaturated -- pharmacology
- Gene Expression -- drug effects
- Humans
- Lung Neoplasms -- genetics
- Macrophages -- cytology
- Matrix Metalloproteinases -- genetics
- Microscopy, Fluorescence
- Neoplasm Invasiveness
- Receptors, Thromboxane A2, Prostaglandin H2 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Sp1 Transcription Factor -- metabolism
- Thromboxane A2 -- pharmacology
- Vascular Endothelial Growth Factor A -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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