Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells. [electronic resource]
Producer: 20130917Description: 939-54 p. digitalISSN:- 1873-3913
- Antioxidants -- pharmacology
- Cell Line, Tumor
- Down-Regulation -- drug effects
- Humans
- Imidazoles -- pharmacology
- Lung Neoplasms -- metabolism
- Mitogen-Activated Protein Kinase 11 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 14 -- antagonists & inhibitors
- NF-kappa B -- antagonists & inhibitors
- Oxidation-Reduction
- Peptides -- pharmacology
- Phosphorylation -- drug effects
- Pyridines -- pharmacology
- RNA Interference
- RNA, Small Interfering -- metabolism
- Receptor for Advanced Glycation End Products
- Receptors, Immunologic -- metabolism
- Signal Transduction -- drug effects
- Transcription Factor RelA -- metabolism
- Vitamin A -- pharmacology
- alpha-Tocopherol -- pharmacology
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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