Structural insights into aldosterone synthase substrate specificity and targeted inhibition. [electronic resource]
Producer: 20130708Description: 315-24 p. digitalISSN:- 1944-9917
- Aldosterone -- biosynthesis
- Blood Pressure
- Catalysis
- Crystallography, X-Ray
- Cytochrome P-450 CYP11B2 -- antagonists & inhibitors
- Desoxycorticosterone -- chemistry
- Fadrozole -- chemistry
- Humans
- Hypertension
- Models, Molecular
- Protein Structure, Tertiary
- Renin-Angiotensin System
- Steroid 11-beta-Hydroxylase -- metabolism
- Substrate Specificity
- Water-Electrolyte Balance
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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