Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models. [electronic resource]
Producer: 20131211Description: 1581-8 p. digitalISSN:- 1558-1497
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Cells, Cultured
- Cognition Disorders -- drug therapy
- Disease Models, Animal
- Gene Expression Regulation
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria -- drug effects
- Niacinamide -- analogs & derivatives
- Organ Culture Techniques
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
- Pyridinium Compounds
- Transcription Factors -- biosynthesis
- Up-Regulation -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
There are no comments on this title.
Log in to your account to post a comment.