PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer. [electronic resource]
Producer: 20130820Description: e53292 p. digitalISSN:- 1932-6203
- Aged
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Breast Neoplasms -- genetics
- Cell Proliferation
- Class I Phosphatidylinositol 3-Kinases
- Everolimus
- Female
- Gene Expression Regulation, Neoplastic
- Genotype
- Humans
- Letrozole
- Middle Aged
- Mutation
- Nitriles -- administration & dosage
- Phosphatidylinositol 3-Kinases -- genetics
- Receptors, Estrogen -- metabolism
- Sirolimus -- administration & dosage
- TOR Serine-Threonine Kinases -- metabolism
- Triazoles -- administration & dosage
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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